epilepticus . treatment of neonatal status Chlormethiazole in the
نویسنده
چکیده
Intermittent convulsions occur in 1% of neonates (O'Donohoe, 1979); status epilepticus is a less common problem. Drugs that are routinely used to control status epilepticus include phenobarbitone, phenytoin, diazepam and paraldehyde, together with the correction of any metabolic defect. We report a case of a newborn infant who had convulsions which were extremely resistant to conventional treatment and which only responded to an intravenous infusion of chlormethiazole.
منابع مشابه
Chlormethiazole in treatment of status epilepticus.
Chlormethiazole (Heminevrin) was successful in controlling fits in seven out of nine episodes of intractable status epilepticus. It was administered as a constant intravenous injection at rates of up to 0.7g/h. No serious side effects were encountered, and the drug deserves wider recognition as a useful therapeutic agent in the management of status epilepticus.
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Background: In this study, we compared the efficacy and safety of propofol and midazolam in treatment of children’s refractory status epilepticus. Methods: We recruited 32 patients with refractory status epilepticus. Of those, 16 were treated primarily with midazolam and 16 received propofol. Results: We achieved complete seizure control in 6 (38%) patients treated by midazolam, and in 10 (63%)...
متن کاملDiagnosis and treatment of status epilepticus on a neurological intensive care unit.
Status epilepticus refractory to first-line therapy is associated with a high morbidity and mortality. Correct diagnosis and adequate treatment of this condition require electrographic monitoring and anaesthetic facilities available in specialist intensive care units (ICUs). We carried out an audit of 26 patients admitted to a neurological ICU with a diagnosis of status epilepticus, to identify...
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Background: Reproductive dysfunction and endocrine disorders are common among men with complex partial seizures of temporal lobe origin. More than 90% of men with epilepsy have abnormal semen analysis, including decreased sperm count, abnormal morphology, and impaired motility. The aim of this study was the assay of chronic treatment with melatonin during the latent phase and chronic phase of e...
متن کاملصرع پایدار مقاوم در کودکان، عوامل خطر، درمان و سرانجام زودرس
Introduction: Refractory status epilepticus is a life-threatening disease in children wherein seizure movements don't response to first line anti convulsion drugs. This study reviewed risk factors, management and early outcome of children with refractory status epilepticus. Methods: Patients with refractory status epilepticus admitted in Tabriz children's hospital between 2003 and 2006 were re...
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تاریخ انتشار 2008